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Dietary carotenoids and vitamins A, C, and E and risk of breast cancer. Cancer Causes Control 1994;5(1):66-72. Kumar B, Cole WC, Prasad KN. 2013 Apr 6;51(3):195-8. View abstract. Cautions. View abstract. 2011;24(2):244-275. It is also used to improve memory and muscle strength. The NNIPS-2 Study Group. Diet and asthma. View abstract. Nutrients. View abstract. 2014 Dec 9;111(12):2220-3. View abstract. A randomized, double-blind, controlled trial. Leppala JM, Virtamo J, Fogelholm R, et al. View abstract. A., Darby, F. J., Zarembski, P., Johnson, B. E., and Frain-Bell, W. The treatment of erythropoietic protoporphyria. Effect of daily vitamin E and multivitamin-mineral supplementation on acute respiratory tract infections in elderly persons: a randomized controlled trial. 6-6-1990;82(11):941-946. View abstract. Int.J.Cancer 1-30-1998;75(3):362-367. View abstract. View abstract. Zinc plus beta-carotene supplementation of pregnant women is superior to beta-carotene supplementation alone in improving vitamin A status in both mothers and infants. Koonsvitsky BP, Berry DA, et al. View abstract. View abstract. Controlled trial of alpha-tocopherol and beta-carotene supplements on stroke incidence and mortality in male smokers. View abstract. Graat JM, Schouten EG, Kok FJ. The ATBC Cancer Prevention Study Group. Huang, H. Y., Caballero, B., Chang, S., Alberg, A. J., Semba, R. D., Schneyer, C. R., Wilson, R. F., Cheng, T. Y., Vassy, J., Prokopowicz, G., Barnes, G. J., and Bass, E. B. View abstract. 2001;10(10):1029-1035. Coodley, G. O., Coodley, M. K., Lusk, R., Green, T. R., Bakke, A. C., Wilson, D., Wachenheim, D., Sexton, G., and Salveson, C. Beta-carotene in HIV infection: an extended evaluation. View abstract. Hercberg, S., Ezzedine, K., Guinot, C., Preziosi, P., Galan, P., Bertrais, S., Estaquio, C., Briancon, S., Favier, A., Latreille, J., and Malvy, D. Antioxidant supplementation increases the risk of skin cancers in women but not in men. Renner, S., Rath, R., Rust, P., Lehr, S., Frischer, T., Elmadfa, I., and Eichler, I. Br.J.Cancer 3-4-2002;86(5):698-701. Cochrane.Database.Syst.Rev. Beta-carotene and other carotenoids as antioxidants. Lin, J., Cook, N. R., Albert, C., Zaharris, E., Gaziano, J. M., Van, Denburgh M., Buring, J. E., and Manson, J. E. Vitamins C and E and beta carotene supplementation and cancer risk: a randomized controlled trial. 2001;40(4):178-184. 2011;(3):CD007749. View abstract. Schroder, H., Navarro, E., Mora, J., Galiano, D., and Tramullas, A. Age-Related Eye Disease Study Research Group. Cancer Causes Control 2009;20(5):691-698. III. 2010;221(2):160-71. Prakash P, Russell RM, Krinsky NI. Insufficient Evidence to Rate Effectiveness for... What other names is Beta-carotene known by? J.Natl.Cancer Inst. Physical activity and the common cold in men administered vitamin E and beta-carotene. Thorax 2009;64(7):610-619. BJU Int 2004;93:1139-50. Kubo, A. and Corley, D. A. Meta-analysis of antioxidant intake and the risk of esophageal and gastric cardia adenocarcinoma. 2006;90(7):847-851. View abstract. 2008;(1):CD006751. Cancer Res. Zhang, X., Dai, B., Zhang, B., and Wang, Z. Vitamin A and risk of cervical cancer: a meta-analysis. View abstract. View abstract. Are there any interactions with medications? Zhang S, Hunter DJ, Forman MR, et al. 0. View abstract. van Leeuwen R, Boekhoorn S, Vingerling JR, et al. Acta Paediatr. Frieling UM, Schaumberg DA, Kupper TS, et al. Alberg AJ, Chen JC, Zhao H, et al. Sesso, H. D., Buring, J. E., Christen, W. G., Kurth, T., Belanger, C., MacFadyen, J., Bubes, V., Manson, J. E., Glynn, R. J., and Gaziano, J. M. Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. 2006;(4):CD001829. View abstract. Sankaranarayanan, R., Mathew, B., Varghese, C., Sudhakaran, P. R., Menon, V., Jayadeep, A., Nair, M. K., Mathews, C., Mahalingam, T. R., Balaram, P., and Nair, P. P. Chemoprevention of oral leukoplakia with vitamin A and beta carotene: an assessment. Proc Nutr Soc 2005;64(4):543-553. Stahl W, Heinrich U, Jungmann H, et al. View abstract. View abstract. View abstract. Mathews-Roth, M. M., Pathak, M. A., Fitzpatrick, T. B., Harber, L. H., and Kass, E. H. Beta carotene therapy for erythropoietic protoporphyria and other photosensitivity diseases. Some side effects may not be reported. Bath-Hextall, F., Leonardi-Bee, J., Somchand, N., Webster, A., Delitt, J., and Perkins, W. Interventions for preventing non-melanoma skin cancers in high-risk groups. Prince, M. I., Mitchison, H. C., Ashley, D., Burke, D. A., Edwards, N., Bramble, M. G., James, O. F., and Jones, D. E. Oral antioxidant supplementation for fatigue associated with primary biliary cirrhosis: results of a multicentre, randomized, placebo-controlled, cross-over trial. 2005;95(7):1075-1096. Exp.Eye Res. View abstract. Cook, N. R., Albert, C. M., Gaziano, J. M., Zaharris, E., MacFadyen, J., Danielson, E., Buring, J. E., and Manson, J. E. A randomized factorial trial of vitamins C and E and beta carotene in the secondary prevention of cardiovascular events in women: results from the Women's Antioxidant Cardiovascular Study. 2003;83(4):277-281. View abstract. Arch Ophthalmol 2003;121:1621-4. View abstract. Amyotroph Lateral Scler Frontotemporal Degener. Christian P, West KP Jr, Khatry SK, et al. 11. Song, Y., Cook, N. R., Albert, C. M., Van, Denburgh M., and Manson, J. E. Effects of vitamins C and E and beta-carotene on the risk of type 2 diabetes in women at high risk of cardiovascular disease: a randomized controlled trial. View abstract. High levels of plasma beta carotene (hypercarotenemia) have not been associated … Incidence of cataract operations in Finnish male smokers unaffected by alpha tocopherol or beta carotene supplements. Arch Intern Med 2004;164:2335-42. 11-1-1990;50(21):6836-6840. Loane, E., Kelliher, C., Beatty, S., and Nolan, J. M. The rationale and evidence base for a protective role of macular pigment in age-related maculopathy. View abstract. Cortes-Jofre, M., Rueda, J. R., Corsini-Munoz, G., Fonseca-Cortes, C., Caraballoso, M., and Bonfill, Cosp, X. Clinical aspects and therapy]. View abstract. While vitamin A, a fat-soluble nutrient, can be toxic if taken in excess, … Overdosage of beta-carotene can cause health hazards like lung cancer, prostate cancer or stomach cancer. 4. Antioxidant vitamin and mineral supplementation and prostate cancer prevention in the SU.VI.MAX trial. Bonifant, C. M., Shevill, E., and Chang, A. MacLennan, R., Macrae, F., Bain, C., Battistutta, D., Chapuis, P., Gratten, H., Lambert, J., Newland, R. C., Ngu, M., Russell, A., and . View abstract. View abstract. 1985;14(2):165-168. Omenn GS, Goodman GE, Thornquist MD, et al. Am J Clin Nutr 2000;71:1187-93. 35. J.Health Popul.Nutr. Nutr Res 2001;21:551-67. The deeper the color, the higher the beta-carotene content (x, x, x). View abstract. View abstract. Exp.Dermatol. View abstract. It is also used to treat chronic fatigue syndrome, aging skin, AIDS, alcoholism, Alzheimer's disease, depression, diabetes, epilepsy, headache, heartburn, a bacterial infection that may cause ulcers (Helicobacter pylori infection), high blood pressure, infertility, Parkinson's disease, rheumatoid arthritis, schizophrenia, stroke, and skin disorders including psoriasis and vitiligo. Chin Med.J.(Engl.) Virtamo J, Pietinen P, Huttunen JK, et al. Low antioxidant vitamin intakes are associated with increases in adverse effects of chemotherapy in children with acute lymphoblastic leukemia. Tauler, P., Aguilo, A., Fuentespina, E., Tur, J. Med.Sci.Sports Exerc. View abstract. Paediatr.Perinat.Epidemiol. N Engl J Med 1996;334:1150-5. Arterioscler Thromb Vasc Biol 2000;20:230-5. Effects of beta-carotene supplementation for six months on clinical and laboratory parameters in patients with cystic fibrosis. View abstract. Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health Study. Dietary antioxidants and peripheral arterial disease: the Rotterdam study. J Nutr 1998;128:1920-6.. View abstract. View abstract. Lee IM, Cook NR, Gaziano JM, et al. 2004;11(5):401-412. Jiang, L., Yang, K. H., Tian, J. H., Guan, Q. L., Yao, N., Cao, N., Mi, D. H., Wu, J., Ma, B., and Yang, S. H. Efficacy of antioxidant vitamins and selenium supplement in prostate cancer prevention: a meta-analysis of randomized controlled trials. Arch.Intern.Med. View abstract. These are the side effects of carrots you need to be wary about. Swanbeck, G. and Wennersten, G. Treatment of polymorphous light eruptions with beta-carotene. Am J Digestive Dis 1952;19:344-8. The alpha-tocopherol, beta-carotene lung cancer prevention study: design, methods, participant characteristics, and compliance. J.Natl.Cancer Inst. View abstract. J Natl Cancer Inst 2007;99:754-64. 9-15-2008;28(6):689-703. View abstract. 1976;20:86-101. Risk factors for lung cancer and for intervention effects in CARET, the Beta-Carotene and Retinol Efficacy Trial. Chemoprevention of gastric dysplasia: randomized trial of antioxidant supplements and anti-Helicobacter pylori therapy. Honarbakhsh, S. and Schachter, M. Vitamins and cardiovascular disease. 2012;11:CD000254. J Nutr 2003;133(1):98-101. 7-22-1977;102(29):1051-1055. J Am Coll Nutr 2001;20(3):232-238. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. Hemila, H., Virtamo, J., Albanes, D., and Kaprio, J. Cooper DA, Eldridge AL, Peters JC. Cooper, K., Squires, H., Carroll, C., Papaioannou, D., Booth, A., Logan, R. F., Maguire, C., Hind, D., and Tappenden, P. Chemoprevention of colorectal cancer: systematic review and economic evaluation. Cancer Causes Control 2010;21(11):1745-1757. Six-year supplementation with alpha-tocopherol and beta-carotene and age-related maculopathy. Beta-carotene is used to prevent certain cancers, heart disease, cataracts, osteoarthritis, and age related macular degeneration (AMD). Int.J.Cancer 2-15-2006;118(4):970-978. 2012;124(2):366-373. J Am Coll Nutr 2001;20:628-36. In Vivo 2007;21(2):189-204. 1986;188(1):20-22. A-Beta-Carotene, A-Bêta-Carotène, Beta Carotene, Bêta-Carotène, Bêta-Carotène Tout Trans, Beta-Caroteno, Carotenes, Carotènes, Carotenoids, Caroténoïdes, Caroténoïdes Mélangés, Mixed Carotenoids, Provitamin A, Provitamine A. Beta-carotene is one of a group of red, orange, and yellow pigments called carotenoids. View abstract. 2009;90(2):429-437. View abstract. View abstract. Cancer Epidemiol.Biomarkers Prev. View abstract. Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. View abstract. Fam.Pract. Cobanoglu, N., Ozcelik, U., Gocmen, A., Kiper, N., and Dogru, D. Antioxidant effect of beta-carotene in cystic fibrosis and bronchiectasis: clinical and laboratory parameters of a pilot study. Other brands: A-Caro-25, B-Caro-T, Caroguard, Lumitene. Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. View abstract. 11-12-2007;167(20):2184-2190. Am.J.Gastroenterol. Respirology. Klin.Monbl.Augenheilkd. Diabetologia 2009;52(10):2117-2121. Wilderness.Environ.Med. 1977;113(9):1229-1232. JAMA 5-20-1974;228(8):1004-1008. Ingesting beta carotene from food sources is generally considered safe but may cause the skin to turn yellow or orange, a condition called carotenosis. 1994;4(1):1-10. The effect of alpha-tocopherol and beta-carotene supplementation on COPD symptoms. 5-21-2003;95(10):717-722. Ophthalmology. 1997;33(4):231-236. Br J Cancer. View abstract. View abstract. Beta carotene is a red-orange pigment found in plants and fruits, especially colorful vegetables. View abstract. Dermatology. 2009;101(8):1113-1131. JAMA 1961;175:187-90. McKeever, T. M. and Britton, J. Evans, J. R. and Lawrenson, J. G. Antioxidant vitamin and mineral supplements for preventing age-related macular degeneration. J Natl Cancer Inst 1996;88:1560-70. Nutr.Res.Rev. Beta carotene is one of the (nearly) 600 different carotenoids —plant pigments that give red/orange fruits and vegetables their color. View abstract. J.Photochem.Photobiol.B 1996;33(2):157-162. Oral zinc in macular degeneration. 2012;17(1):1-15. Garbagnati, F., Cairella, G., De, Martino A., Multari, M., Scognamiglio, U., Venturiero, V., and Paolucci, S. Is antioxidant and n-3 supplementation able to improve functional status in poststroke patients? Cheung MC, Zhao XQ, Chait A, et al. Antioxidant consumption and risk of coronary heart disease: emphasis on vitamin C, vitamin E, and beta-carotene: A statement for healthcare professionals from the American Heart Association. Br.J.Dermatol. Cochrane.Database.Syst.Rev. Lee, T. and Dugoua, J. J. Nutritional supplements and their effect on glucose control. View abstract. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. [Erythropoietic protoporthyria. View abstract. Am J Clin Nutr 2000;72:1421-3. View abstract. View abstract. Food Standards Agency. View abstract. Teikari JM, Laatikainen L, Virtamo J, et al. J Natl Cancer Inst 1995;87:1767-76. 1999;18(5):426-33. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Your skin may turn a yellow color while taking beta-carotene. View abstract. 1987;88(3 Suppl):32s-38s. A., Gao, Y. T., Goodman, M. T., Hallmans, G., Helzlsouer, K. J., Hoffman-Bolton, J., Hulten, K., Sesso, H. D., Sowell, A. L., Tamimi, R. M., Toniolo, P., Wilkens, L. R., Winkvist, A., Zeleniuch-Jacquotte, A., Zheng, W., and Hankinson, S. E. Circulating carotenoids and risk of breast cancer: pooled analysis of eight prospective studies. Am.J.Clin.Nutr. Pryor WA, Stahl W, Rock CL. 2007;55(1):35-42. Plummer, M., Vivas, J., Lopez, G., Bravo, J. C., Peraza, S., Carillo, E., Cano, E., Castro, D., Andrade, O., Sanchez, V., Garcia, R., Buiatti, E., Aebischer, C., Franceschi, S., Oliver, W., and Munoz, N. Chemoprevention of precancerous gastric lesions with antioxidant vitamin supplementation: a randomized trial in a high-risk population. View abstract. Consuming more than 20 milligrams of beta-carotene every day for a few weeks can cause skin discoloration . View abstract. View abstract. O'Neil, C., Shevill, E., and Chang, A. Effects of a combination of beta-carotene and vitamin A on lung cancer and cardiovascular disease. Studies show that the water-based version seems to be absorbed better. View abstract. However, the safety of high-dose beta-carotene supplements in pregnancy and lactation has not been well-studied. Beta carotene: from biochemistry to clinical trials. Eur.J.Clin.Nutr. View abstract. View abstract. View abstract. Possible Side Effects of Beta-Carotene: Early Concerns About Antioxidant Side Effects. View abstract. The name is derived from the Latin word for carrot. 2012;131(1):239-253. 1980;60(3):251-255. Skin Pharmacol Appl.Skin Physiol 2002;15(5):307-315. Michaud, D. S., Pietinen, P., Taylor, P. R., Virtanen, M., Virtamo, J., and Albanes, D. Intakes of fruits and vegetables, carotenoids and vitamins A, E, C in relation to the risk of bladder cancer in the ATBC cohort study. View abstract. View abstract. Circulation 1999;99:591-5. A., and Pons, A. Kopcke, W. and Krutmann, J. J Natl.Cancer Inst. View abstract. 2008;(1):CD000253. Am J Clin Nutr 2001;73:1045-51. View abstract. View abstract. Effect of palm oil carotene on breast cancer tumorigenicity in nude mice. Stur M, Tittl M, Reitner A, Meisinger V. Oral zinc and the second eye in age-related macular degeneration. Proc.Nutr.Soc. Washington, DC: National Academy Press, 2000. Chong, E. W., Wong, T. Y., Kreis, A. J., Simpson, J. N Engl J Med 1997;337:365-372.. View abstract. Vitamin E and Beta Carotene supplementation in high risk for stroke: a subgroup analysis of the alpha-tocopherol, beta-carotene cancer prevention study. Lipids 2002;37:557-60. Probucol and multivitamins in the prevention of restenosis after coronary angioplasty. Girodon F, Lombard M, Galan P, et al. Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of baseline characteristics and study compliance. Am J Epidemiol 2001;154:145-9.. View abstract. Cho, E., Hunter, D. J., Spiegelman, D., Albanes, D., Beeson, W. L., van den Brandt, P. A., Colditz, G. A., Feskanich, D., Folsom, A. R., Fraser, G. E., Freudenheim, J. L., Giovannucci, E., Goldbohm, R. A., Graham, S., Miller, A. Cancer Causes Control 2000;11(9):859-867. Tree nut phytochemicals: composition, antioxidant capacity, bioactivity, impact factors. Paiva SA, Russell RM. A systematic review of almonds, Brazils, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts. Even as super nutrients with a lot of health benefits, Beta-Carotene is not without side effects, especially the supplement products. Cochrane.Database.Syst.Rev. Bjelakovic G, Nikolova D, Simonetti RG, Gluud C. Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis. View abstract. Niacin can increase good cholesterol levels. Zhu, S., Mason, J., Shi, Y., Hu, Y., Li, R., Wahg, M., Zhou, Y., Jin, G., Xie, Y., Wu, G., Xia, D., Qian, Z., Sohg, H., Zhang, L., Russell, R., and Xiao, S. The effect of folic acid on the development of stomach and other gastrointestinal cancers. Wang A, Han J, Jiang Y, Zhang D. Association of vitamin A and ß-carotene with risk for age-related cataract: a meta-analysis. 2010;(12):CD007020. Blumberg, J. and Block, G. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study in Finland. Vitamin A or beta-carotene supplementation reduces but does not eliminate maternal night blindness in Nepal. In addition, there is also concern that taking large amounts of a multivitamin plus a separate beta-carotene supplement increases the chance of developing advanced prostate cancer in men. 2007;102(10):2323-2330. Li, F. J., Shen, L., and Ji, H. F. Dietary intakes of vitamin E, vitamin C, and beta-carotene and risk of Alzheimer's disease: a meta-analysis. But as discussed, eating too many of them in a day is a problem. Mathew, M. C., Ervin, A. M., Tao, J., and Davis, R. M. Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract. View abstract. View abstract. de, Selys R., Decroix, J., Frankart, M., Hassoun, A., Willocx, D., Pirard, C., and Bourlond, A. Corbett, M. F., Herxheimer, A., Magnus, I. Circulation 2004;110:637-41. Ann.Med. Age related macular degeneration--should your patients be taking additional supplements? 0. View abstract. 2015 Dec;54(8):1371-8. Kennedy DD, Tucker KL, Ladas ED, et al. View abstract. Int.J.Dermatol. Oral mucositis for patients with recurrent polyserositis ( Familial Mediterranean beta-carotene side effects ) the! 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